Natural Progesterone

The liposome-mediated delivery system used in ProBalance™ carries the progesterone directly into the bloodstream, bypassing the metabolic processes required by other transdermals.

"The signs and symptoms of osteoporosis cleared in every patient using progesterone cream and incidence of fractures dropped to zero." - John R. Lee, M.D.

Reduces the symptoms and discomfort of PMS, premenopause and menopause without the side effects often associated with synthetic hormone replacement therapy.

Hormone replacement is routinely advised by gynecologists for menopausal women, most commonly as protection against osteoporosis and relief from menopausal symptoms such as hot flashes. For most women, hormone replacement is synonymous with estrogen replacement.

Estrogen is not a hormone, but a class of hormones produced by the ovaries, the major members being estrone, estradiol, and estriol. Estrogen is important for childbearing and survival of the fetus. Menopause signals the end of a woman's childbearing years so it follows that estrogen levels would decrease. The question is, do women need estrogen replacement?

Progestins such as Provera ® , are synthetic progesterones, synthesized from natural progesterone, but because the structure is altered, there is a long list of side effects including mental depression, insomnia, cervical erosion, edema, acne and pulmonary embolism. When taken in combination with estrogens, a woman may experience nervousness, dizziness, hair loss, fatigue, or hypertension, to name a few. Although many doctors believe that there is no difference between synthetic and natural progesterone, some synthetic progesterones can produce masculinizing effects in women whereas natural progesterone does not cause masculinization.

Transdermal absorption of natural progesterone has been established as an effective and safe delivery method. Rubbed into thin-skinned areas such as the palms of the hands, face, neck, breasts, inner arms, or soles of the feet, the progesterone is absorbed into the skin and stored in the fatty tissues. It is then taken into the bloodstream where it circulates to receptor sites throughout the body.

ProBalance™ is a fragrance free cream containing 2% natural progesterone. The unique liposome-mediated delivery system carries the progesterone through the skin directly to the bloodstream. For most women, hormone balance is achieved by gently rubbing the cream into thin-skinned areas twice a day in monthly cycles of three weeks on and one week off. For detailed use in monthly cycles of three weeks on and one week off. For detailed use information, refer to the following books by John R. Lee, M.D.:

• Natural Progesterone:
• The Multiple Roles of a Remarkable Hormone
• What Your Doctor May Not Tell You About Menopause

Using ProBalance™

The information herein is for general use and not intended to encourage self diagnosis, self treatment or replace the guidance of your health professional.

For PMS and premenopausal symptoms, begin using the cream 10 to 12 days after the first day of your period. Apply the cream twice a day from either Day 10 or 12 through Day 26 or 48 hours before the scheduled start of next period. If your period starts early, stop using the cream – Mother Nature is trying to balance your hormone levels. When your period starts count forward 12 days (10 if you normally have a shorter cycle than 28 days) and begin the program on that day. Be patient, it may take three cycles before you achieve synchrony with your normal cycle. If you have cramps, headache, swollen breasts, etc., the cream may be applied directly to the problem area.

Menopausal women not taking estrogen have a wider latitude in using the cream. For convenience, you may choose a dosage schedule based on the calendar month. Use the cream twice a day from the 1st to the 14th or 21st of each month and none from the 15th or 22nd to the end of the month. Some women report that using a larger dab of cream at night helps them sleep better.

Menopausal women taking estrogen should reduce their dosage by half when starting to use progesterone cream. This is important because in women deficient in progesterone, the cream may temporarily increase the sensitivity of estrogen receptors. If estrogen intake is not reduced, you may experience symptoms of estrogen dominance during the first couple of months. You may try lowering your estrogen dose by half again every two to three months. (The estrogen dose should be low enough that monthly bleeding does not occur, but high enough to prevent vaginal dryness and hot flashes.) Estrogen and progesterone can be used together for up to 25 days each month, with 7 days without either hormone.

Menopausal women taking an estrogen and progestin combination should refer to Dr. John Lee's book, What Your Doctor May Not Tell You About Menopause.

Ingredients:
Deionized Water, Capryllic Capric Triglycerides, Simulgel (Plant based thickener), Progesterone, Glycerin, Grapefruit Seed Extract, Liposomes, Vitamin E Acetate, Contains no artificial flagrance or coloring.

• Natural Progesterone: The Multiple Roles of a Remarkable Hormone, John R. Lee, MD, BLL Publishing, P.O. Box 2068, Sebastopol, CA 95473.
• What's Wrong with My Hormones?, Gillian Ford, Desmond Ford Publications, 7955 Bullard Drive, Newcastle, CA 95658, 1992.
• My Body, My Health: The Concerned Woman's Guide to Gynecology; Felicia Stewart MD, Felicia Guest, Gary Stewart MD, and Robert Hatcher MD, John Wiley & Sons, 1979.
• PMS: Premenstrual Syndrome and You, Neils Lauersen, MD, Simon & Schuster, 1983.

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